This Cyber Security Framework for Autonomous Machines is offered as a high-level security and compliance requirements guide for developers creating autonomous machines including future connected cars, robots, medical devices, and industrial controllers. The framework is written in an abstract manner so that it can address each of these diverse areas without imposing specific design decisions. The framework is written in the style of the NIST 800-53 Rev 4 Cybersecurity Framework to simplify its application and use, perhaps as an appendix to any NIST assessment for a computing entity with autonomous machine characteristics.